Leslie Popplewell, MD, FACP, describes how engineered toxin bodies work as an anti-cancer treatmentPart ofASH Annual Meeting & ExpositionDec 16, 20202 Min WatchUp NextLeslie Popplewell, MD, FACP, on the future of CAR T-cell therapies in follicular lymphomaUp NextLeslie Popplewell, MD, FACP, discusses the latest treatment trends in follicular lymphomaUp NextFrederick Locke, MD, shares thoughts on the evolution of bispecific antibodiesDescriptionCopy LinkDr. Popplewell, Associate Clinical Professor of Hematology & Hematopoietic Cell Transplantation, Hematologist/Oncologist, City of Hope, describes how engineered toxin bodies (EBTs) work as an anti-cancer treatment Show More© 2025 HealthCentral LLC. All rights reserved.Copy LinkASH Annual Meeting & ExpositionMyelodysplastic Syndromes (MDS)Smoking Tied to MDS Mutations and Poor SurvivalYoussef RddadNews3 Min ReadSmoking history in patients with myelodysplastic syndromes was tied to distinct genetic mutations, higher mutation burden, and worse survival in new data. Myelodysplastic Syndromes (MDS)Smoking Tied to MDS Mutations and Poor SurvivalYoussef RddadNews3 Min ReadSmoking history in patients with myelodysplastic syndromes was tied to distinct genetic mutations, higher mutation burden, and worse survival in new data. Multiple MyelomaHigh-Fiber Diet May Slow Myeloma ProgressionYoussef RddadNews4 Min ReadHigh-fiber diets may slow disease progression in precursor conditions of multiple myeloma and reduce complications after stem cell transplantation. Multiple MyelomaHigh-Fiber Diet May Slow Myeloma ProgressionYoussef RddadNews4 Min ReadHigh-fiber diets may slow disease progression in precursor conditions of multiple myeloma and reduce complications after stem cell transplantation. Multiple MyelomaDo New Smoldering Myeloma Data Justify Treatment?Leah LawrenceNews4 Min ReadDaratumumab reduced the risk for progression or death compared with active monitoring among patients with high-risk smoldering multiple myeloma, new data show. Multiple MyelomaDo New Smoldering Myeloma Data Justify Treatment?Leah LawrenceNews4 Min ReadDaratumumab reduced the risk for progression or death compared with active monitoring among patients with high-risk smoldering multiple myeloma, new data show. Non-Hodgkin's Lymphoma (NHL)No Transplant Needed for Mantle Cell Lymphoma?Leah LawrenceNews3 Min ReadSome patients with mantle cell lymphoma do not benefit from consolidative autologous hematopoietic stem cell transplant, according to new data from ASH 2024. Non-Hodgkin's Lymphoma (NHL)No Transplant Needed for Mantle Cell Lymphoma?Leah LawrenceNews3 Min ReadSome patients with mantle cell lymphoma do not benefit from consolidative autologous hematopoietic stem cell transplant, according to new data from ASH 2024. Non-Hodgkin's Lymphoma (NHL)More Treatments for Indolent Lymphoma Soon?Andrew M. Evens, DO, MSc, FACPVideoFrom data that may soon lead to an approval in follicular lymphoma, to a pair of phase 2 trials, here are some key studies on indolent lymphomas from ASH 2024. Non-Hodgkin's Lymphoma (NHL)More Treatments for Indolent Lymphoma Soon?Andrew M. Evens, DO, MSc, FACPVideoFrom data that may soon lead to an approval in follicular lymphoma, to a pair of phase 2 trials, here are some key studies on indolent lymphomas from ASH 2024. Non-Hodgkin's Lymphoma (NHL)Practice Change in R/R Follicular Lymphoma?Leah LawrenceNews3 Min ReadAdding tafasitamab to lenalidomide plus rituximab significantly improves PFS in patients with relapsed or refractory follicular lymphoma, new data show. Non-Hodgkin's Lymphoma (NHL)Practice Change in R/R Follicular Lymphoma?Leah LawrenceNews3 Min ReadAdding tafasitamab to lenalidomide plus rituximab significantly improves PFS in patients with relapsed or refractory follicular lymphoma, new data show. Chronic Lymphocytic Leukemia (CLL)Bispecific Has High Response Rates in CLL TrialLeah LawrenceNewsUse of epcoritamab resulted in an encouraging rate of complete remission and undetectable minimal residual disease in a small study of heavily pretreated R/R CLL. Chronic Lymphocytic Leukemia (CLL)Bispecific Has High Response Rates in CLL TrialLeah LawrenceNewsUse of epcoritamab resulted in an encouraging rate of complete remission and undetectable minimal residual disease in a small study of heavily pretreated R/R CLL. Acute Myelogenous Leukemia (AML)Barriers to Lifesaving Treatment for AML RevealedLeah LawrenceNews3 Min ReadA patient’s socioeconomic status can significantly affect their likelihood of receiving an allogeneic hematopoietic transplant for AML, according to new data. Acute Myelogenous Leukemia (AML)Barriers to Lifesaving Treatment for AML RevealedLeah LawrenceNews3 Min ReadA patient’s socioeconomic status can significantly affect their likelihood of receiving an allogeneic hematopoietic transplant for AML, according to new data. Chronic Lymphocytic Leukemia (CLL)Can CAR-T Cure Chronic Lymphocytic Leukemia?Youssef RddadNews3 Min ReadCAR-T therapy may offer durable disease control and a potential path to cure for some patients with relapsed/refractory CLL, according to new long-term data. Chronic Lymphocytic Leukemia (CLL)Can CAR-T Cure Chronic Lymphocytic Leukemia?Youssef RddadNews3 Min ReadCAR-T therapy may offer durable disease control and a potential path to cure for some patients with relapsed/refractory CLL, according to new long-term data. Chronic Lymphocytic Leukemia (CLL)Acalabrutinib Plus Venetoclax Improves PFS in CLLYoussef RddadNews4 Min ReadAcalabrutinib plus venetoclax, with or without obinutuzumab, improves PFS in patients with untreated CLL compared with chemoimmunotherapy, new data show. Chronic Lymphocytic Leukemia (CLL)Acalabrutinib Plus Venetoclax Improves PFS in CLLYoussef RddadNews4 Min ReadAcalabrutinib plus venetoclax, with or without obinutuzumab, improves PFS in patients with untreated CLL compared with chemoimmunotherapy, new data show. Chronic Lymphocytic Leukemia (CLL)How Community Clinics Are Using Venetoclax in CLLYoussef RddadNews4 Min ReadA survey of community-based cancer providers indicated that many have developed practices to address challenges in initiating venetoclax for patients with CLL. Chronic Lymphocytic Leukemia (CLL)How Community Clinics Are Using Venetoclax in CLLYoussef RddadNews4 Min ReadA survey of community-based cancer providers indicated that many have developed practices to address challenges in initiating venetoclax for patients with CLL. Acute Lymphocytic LeukemiaBispecific Combo New Standard in Pediatric ALLYoussef RddadNews3 Min ReadBlinatumomab plus standard chemotherapy improves disease-free survival in pediatric patients with newly diagnosed B-cell acute lymphoblastic leukemia. Acute Lymphocytic LeukemiaBispecific Combo New Standard in Pediatric ALLYoussef RddadNews3 Min ReadBlinatumomab plus standard chemotherapy improves disease-free survival in pediatric patients with newly diagnosed B-cell acute lymphoblastic leukemia.